Tag

Light
Sahel, JA., Boulanger-Scemama, E., Pagot, C. et al. Partial recovery of visual function in a blind patient after optogenetic therapy. Nat Med (2021). https://doi.org/10.1038/s41591-021-01351-4 Abstract Optogenetics may enable mutation-independent, circuit-specific restoration of neuronal function in neurological diseases. Retinitis pigmentosa is a neurodegenerative eye disease where loss of photoreceptors can lead to complete blindness. In a blind patient, we combined...
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Source https://www.pittwire.pitt.edu/news/first-time-optogenetic-therapy-partially-restores-patient-s-vision Optogenetic therapy, or manipulating proteins and cells with light, is an advanced technology developed in the early 2000s that drove major discoveries about the inner workings of our brains. Yet, while actively researched in experimental animals, functional improvement using this method was never reported in humans—until now. In a paper published today in Nature...
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Abulmeaty, M.M.A.; Almajwal, A.M.; Alnumair, K.S.; Razak, S.; Hasan, M.M.; Fawzy, A.; Farraj, A.I.; Abudawood, M.; Aljuraiban, G.S. Effect of Long-Term Continuous Light Exposure and Western Diet on Adropin Expression, Lipid Metabolism, and Energy Homeostasis in Rats. Biology 2021, 10, 413. https://doi.org/10.3390/biology10050413 Simple Summary Behavioral characteristics of living organisms may affect the metabolism and its underlying molecular basis....
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Sriram Murali Being under a sky full of stars makes you feel tiny, humble, kind and caring. But, thanks to light pollution, most people lack this connection. Millions of kids are robbed of finding their passion for Astronomy. We’ve lost the potential for thousands of great minds. We are losing our identity only increasing the...
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Maurice M. Ohayon, MD, DSc, PhD, Cristina Milesi, PhD, Artificial Outdoor Nighttime Lights Associate with Altered Sleep Behavior in the American General Population, Sleep, Volume 39, Issue 6, June 2016, Pages 1311–1320, https://doi.org/10.5665/sleep.5860 Abstract Study Objectives: Our study aims to explore the associations between outdoor nighttime lights (ONL) and sleep patterns in the human population. Methods: Cross-sectional...
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80% of the world’s population live under light polluted skies. What do we lose when we lose sight of the stars? Excessive and improper lighting robs us of our night skies, disrupts our sleep patterns and endangers nocturnal habitats. The current advances in LED technology have enabled several cities to safely light their streets and...
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Alvord VM, Kantra EJ, Pendergast JS. Estrogens and the circadian system. Semin Cell Dev Biol. 2021 May 8:S1084-9521(21)00083-5. doi: 10.1016/j.semcdb.2021.04.010. Epub ahead of print. PMID: 33975754. Abstract Circadian rhythms are ~24 h cycles of behavior and physiology that are generated by a network of molecular clocks located in nearly every tissue in the body. In...
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Harpreet Shinhmar, MSc, Manjot Grewal, BSc, Sobha Sivaprasad, MBBS, PhD, Chris Hogg, Victor Chong, MBBS, PhD, Magella Neveu, PhD, Glen Jeffery, DPhil, Optically Improved Mitochondrial Function Redeems Aged Human Visual Decline, The Journals of Gerontology: Series A, Volume 75, Issue 9, September 2020, Pages e49–e52, https://doi.org/10.1093/gerona/glaa155 Abstract The age spectrum of human populations is shifting toward the...
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Source: https://www.sciencemag.org/news/2021/05/can-scientists-help-insects-survive-their-fatal-attraction-light-night By Elizabeth Pennisi May. 4, 2021 Each summer, on bridges across the world, mayfly massacres occur. First, warm weather prompts the transformation of the insects’ aquatic larvae. Within hours, the short-lived, flying adults pop out of streams, rivers, and lakes, eager to mate and lay eggs by the millions. But bridges illuminated with artificial...
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Mendoza, J. Nighttime Light Hurts Mammalian Physiology: What Diurnal Rodent Models Are Telling Us. Clocks & Sleep 2021, 3, 236-250. https://doi.org/10.3390/clockssleep3020014 Abstract Natural sunlight permits organisms to synchronize their physiology to the external world. However, in current times, natural sunlight has been replaced by artificial light in both day and nighttime. While in the daytime, indoor artificial light...
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