Tag

Circadian Disruption
Nankivell, V.A., Tan, J.T.M., Wilsdon, L.A. et al. Circadian disruption by short light exposure and a high energy diet impairs glucose tolerance and increases cardiac fibrosis in Psammomys obesus. Sci Rep 11, 9673 (2021). https://doi.org/10.1038/s41598-021-89191-7 Abstract Type 2 diabetes mellitus (T2DM) increases cardiac inflammation which promotes the development of cardiac fibrosis. We sought to determine the impact of circadian disruption on...
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BACKGROUND INFORMATION Modern electric lighting enables people to work, sleep, eat, and receive services throughout the 24-hour day. As a result, many individuals encounter new patterns and types of electrical light, change the timing of their meals, and experience sleep disturbances and other stresses. Those factors can disrupt circadian rhythms and possibly lead to adverse...
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April 2021 Summary of NTP Cancer Hazard Conclusions Exposure Circumstances That Cause Circadian Disruption:Persistent Night Shift WorkCertain Lighting Conditions https://ntp.niehs.nih.gov/ntp/results/pubs/cancer_assessment/lanfinal20210400_508.pdf Selected images: NTP Review of Shift Work at Night, Light at Night, and Circadian Disruption Topic Overview Status: NTP cancer hazard assessments Conclusion(s): NTP concluded that (1) persistent night shift work can cause breast cancer in women...
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APRIL 21, 2021 by University of Waterloo https://medicalxpress.com/news/2021-04-shift-work-negative-impacts-health-affects.html Shift-work and irregular work schedules can cause several health-related issues and affect our defense against infection, according to new research from the University of Waterloo. These health-related issues occur because the body’s natural clock, called the circadian clock, can be disrupted by inconsistent changes in the sleep-wake schedule...
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Clarkson-Townsend DA, Bales KL, Marsit CJ, Pardue MT. Light Environment Influences Developmental Programming of the Metabolic and Visual Systems in Mice. Invest Ophthalmol Vis Sci. 2021 Apr 1;62(4):22. doi: 10.1167/iovs.62.4.22. PMID: 33861321. Abstract Purpose: Light is a salient cue that can influence neurodevelopment and the immune system. Light exposure out of sync with the endogenous clock...
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Barca-Mayo O and López M (2021) Astrocyte Clocks and Glucose Homeostasis. Front. Endocrinol. 12:662017. doi: 10.3389/fendo.2021.662017 The endogenous timekeeping system evolved to anticipate the time of the day through the 24 hours cycle of the Earth’s rotation. In mammals, the circadian clock governs rhythmic physiological and behavioral processes, including the daily oscillation in glucose metabolism, food intake,...
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Xiao Q, Jones RR, James P, Stolzenberg-Solomon RZ. Light at Night and Risk of Pancreatic Cancer in the NIH-AARP Diet and Health Study. Cancer Res. 2021 Jan 29:canres.2256.2020. doi: 10.1158/0008-5472.CAN-20-2256. Epub ahead of print. PMID: 33514513. Abstract Circadian disruption may play a role in carcinogenesis. Recent research suggests that light at night (LAN), a circadian...
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Trockel MT, Menon NK, Rowe SG, et al. Assessment of Physician Sleep and Wellness, Burnout, and Clinically Significant Medical Errors. JAMA Netw Open. 2020;3(12):e2028111. doi:10.1001/jamanetworkopen.2020.28111 Key Points Question  Is sleep-related impairment associated with burnout, professional fulfillment, and self-reported clinically significant medical error in physicians? Findings  In this cross-sectional study of 11 395 physicians, sleep-related impairment had statistically significant correlations with...
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Source: https://www.birminghammail.co.uk/news/midlands-news/light-pollution-row-huge-units-19438851 Residents in nearby lane objected to illuminated signs plan By David Irwin, Local Democracy Reporter 11 DEC 2020 Fears that illuminated signs would cause fresh upset for Solihull residents living in a leafy lane has seen strict conditions imposed on plans tabled for the huge units opposite. IAC Group, which is based at...
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Bartman CM, Eckle T. Circadian-Hypoxia Link and its Potential for Treatment of Cardiovascular Disease. Curr Pharm Des. 2019;25(10):1075-1090. doi:10.2174/1381612825666190516081612 Abstract Throughout evolutionary time, all organisms and species on Earth evolved with an adaptation to consistent oscillations of sunlight and darkness, now recognized as ‘circadian rhythm.’ Single-cellular to multi-system organisms use circadian biology to synchronize to the...
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