Tag

Light At Night
Sulli G, Manoogian ENC, Taub PR, Panda S. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends in Pharmacological Sciences. 2018 Sep;39(9):812-827. DOI: 10.1016/j.tips.2018.07.003. Highlights Although circadian rhythm disruption (CRD) was typically considered to be a risk for chronic diseases solely for shift workers (∼20%...
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BACKGROUND INFORMATION Modern electric lighting enables people to work, sleep, eat, and receive services throughout the 24-hour day. As a result, many individuals encounter new patterns and types of electrical light, change the timing of their meals, and experience sleep disturbances and other stresses. Those factors can disrupt circadian rhythms and possibly lead to adverse...
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April 2021 Summary of NTP Cancer Hazard Conclusions Exposure Circumstances That Cause Circadian Disruption:Persistent Night Shift WorkCertain Lighting Conditions https://ntp.niehs.nih.gov/ntp/results/pubs/cancer_assessment/lanfinal20210400_508.pdf Selected images: NTP Review of Shift Work at Night, Light at Night, and Circadian Disruption Topic Overview Status: NTP cancer hazard assessments Conclusion(s): NTP concluded that (1) persistent night shift work can cause breast cancer in women...
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Mendoza, J. Nighttime Light Hurts Mammalian Physiology: What Diurnal Rodent Models Are Telling Us. Clocks & Sleep 2021, 3, 236-250. https://doi.org/10.3390/clockssleep3020014 Abstract Natural sunlight permits organisms to synchronize their physiology to the external world. However, in current times, natural sunlight has been replaced by artificial light in both day and nighttime. While in the daytime, indoor artificial light...
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Szkiela, M.; Kusideł, E.; Makowiec-Dąbrowska, T.; Kaleta, D. How the Intensity of Night Shift Work Affects Breast Cancer Risk. Int. J. Environ. Res. Public Health 2021, 18, 4570. https://doi.org/10.3390/ijerph18094570 Abstract Background—In 2019, the IARC concluded that “night shift work is probably carcinogenic to humans (Group 2A), based on limited evidence from human epidemiological studies and sufficient evidence of...
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Russart KLG, Nelson RJ. Light at night as an environmental endocrine disruptor. Physiol Behav. 2018 Jun 1;190:82-89. doi: 10.1016/j.physbeh.2017.08.029. Epub 2017 Sep 7. PMID: 28870443; PMCID: PMC5839924. https://www.sciencedirect.com/science/article/abs/pii/S0031938417302743?via%3Dihub Abstract Environmental endocrine disruptors (EEDs) are often consequences of human activity; however, the effects of EEDs are not limited to humans. A primary focus over the past...
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Xiao Q, Jones RR, James P, Stolzenberg-Solomon RZ. Light at Night and Risk of Pancreatic Cancer in the NIH-AARP Diet and Health Study. Cancer Res. 2021 Jan 29:canres.2256.2020. doi: 10.1158/0008-5472.CAN-20-2256. Epub ahead of print. PMID: 33514513. Abstract Circadian disruption may play a role in carcinogenesis. Recent research suggests that light at night (LAN), a circadian...
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Cain, S.W., McGlashan, E.M., Vidafar, P. et al. Evening home lighting adversely impacts the circadian system and sleep. Sci Rep 10, 19110 (2020). https://doi.org/10.1038/s41598-020-75622-4 Abstract The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all organisms. In an evolutionary heartbeat, humans have taken control of their light environment with electric light. Humans...
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Every cell in your body connects with just light. Learn what circadian medicine focuses on and where medical efforts are being put to solving some of humanity’s biggest health crises today. From the stars above to the molecular biology that lies at the centre of all living things, Circadian Medicine will help us understand and...
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Abstract Transl Psychiatry. 2017 Jan; 7(1): e1017. Published online 2017 Jan 31. doi: 10.1038/tp.2016.262 Temporal organization of physiology is critical for human health. In the past, humans experienced predictable periods of daily light and dark driven by the solar day, which allowed for entrainment of intrinsic circadian rhythms to the environmental light–dark cycles. Since the adoption...
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