Tag

Circadian
Bellastella G, Maiorino M, Scappaticcio L, et al. Chronothyroidology: Chronobiological Aspects in Thyroid Function and Diseases Life (Basel, Switzerland). 2021 May;11(5). Abstract  Chronobiology is the scientific discipline which considers biological phenomena in relation to time, which assumes itself biological identity. Many physiological processes are cyclically regulated by intrinsic clocks and many pathological events show a...
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Hayter, E.A., Wehrens, S.M.T., Van Dongen, H.P.A. et al. Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia. Nat Commun 12, 2472 (2021). https://doi.org/10.1038/s41467-021-22788-8 Abstract Electrical activity in the heart exhibits 24-hour rhythmicity, and potentially fatal arrhythmias are more likely to occur at specific times of day. Here, we demonstrate that circadian clocks within the brain and heart set...
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Mendoza, J. Nighttime Light Hurts Mammalian Physiology: What Diurnal Rodent Models Are Telling Us. Clocks & Sleep 2021, 3, 236-250. https://doi.org/10.3390/clockssleep3020014 Abstract Natural sunlight permits organisms to synchronize their physiology to the external world. However, in current times, natural sunlight has been replaced by artificial light in both day and nighttime. While in the daytime, indoor artificial light...
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Woller, A.; Gonze, D. Circadian Misalignment and Metabolic Disorders: A Story of Twisted Clocks. Biology 2021, 10, 207. https://doi.org/10.3390/biology10030207AMA Style Simple Summary In mammals, many physiological processes follow a 24 h rhythmic pattern. These rhythms are governed by a complex network of circadian clocks, which perceives external time cues (notably light and nutrients) and adjusts the timing of...
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Cain, S.W., McGlashan, E.M., Vidafar, P. et al. Evening home lighting adversely impacts the circadian system and sleep. Sci Rep 10, 19110 (2020). https://doi.org/10.1038/s41598-020-75622-4 Abstract The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all organisms. In an evolutionary heartbeat, humans have taken control of their light environment with electric light. Humans...
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Merikanto I, Partonen T. Increase in eveningness and insufficient sleep among adults in population-based cross-sections from 2007 to 2017. Sleep Med. 2020 Aug 19;75:368-379. doi: 10.1016/j.sleep.2020.07.046. Epub ahead of print. PMID: 32950882. Abstract Objectives: Short or long sleep duration, insufficient sleep, and Evening chronotype associate with many health issues and increased risk for mortality. Understanding population-level...
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https://www.nature.com/articles/s41586-019-1579-3 Abstract Group 3 innate lymphoid cells (ILC3s) are major regulators of inflammation, infection, microbiota composition and metabolism1. ILC3s and neuronal cells have been shown to interact at discrete mucosal locations to steer mucosal defence2,3. Nevertheless, it is unclear whether neuroimmune circuits operate at an organismal level, integrating extrinsic environmental signals to orchestrate ILC3 responses....
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