Review: Comparing DNA damage induced by mobile telephony and other types of man-made electromagnetic fields

Mutation Research/Reviews in Mutation Research

Volume 781, July–September 2019, Pages 53-62

Dimitris J.Panagopoulosabc

https://doi.org/10.1016/j.mrrev.2019.03.003

Abstract

The number of studies showing adverse effects on living organisms induced by different types of man-made Electromagnetic Fields (EMFs) has increased tremendously. Hundreds of peer reviewed published studies show a variety of effects, the most important being DNA damage which is linked to cancer, neurodegenerative diseases, reproductive declines etc. Those studies that are far more effective in showing effects employ real-life Mobile Telephony (MT) exposures emitted by commercially available mobile phones. The present review – of results published by my group from 2006 until 2016 – compares DNA fragmentation induced by six different EMFs on the same biological system – the oogenesis of Drosophila melanogaster – under identical conditions and procedures. Such a direct comparison between different EMFs – especially those employed in daily life – on the same biological endpoint, is very useful for drawing conclusions on their bioactivity, and novel. It shows that real MT EMFs are far more damaging than 50 Hz alternating magnetic field (MF) – similar or much stronger to those of power lines – or a pulsed electric field (PEF) found before to increase fertility. The MT EMFs were significantly more bioactive even for much shorter exposure durations than the other EMFs. Moreover, they were more damaging than previously tested cytotoxic agents like certain chemicals, starvationdehydration. Individual parameters of the real MT EMFs like intensity, frequency, exposure duration, polarization, pulsing, modulation, are discussed in terms of their role in bioactivity. The crucial parameter for the intense bioactivity seems to be the extreme variability of the polarized MT signals, mainly due to the large unpredictable intensity changes.

Note added by EMFSA:

Dr. George Carlo: “This new paper by Dr. Panagopoulos clearly describes and documents the mechanistic aspects that underscore why man-made, polarized waveforms can cause so many different types of adverse biological effects. This is key. While focused on genetic outcomes, the impact triggers described in the paper apply across the board to organelles, cells, tissues, organs and organ systems. This is a foundation that will be key to any and all risk assessments as well as derivations of any and all safety standards.

Last paragraph of conclusion of paper: “The present study further confirms my previous results and conclusions that experiments should employ real-life and not simulated EMFs, and human/animal exposure to microwave telecommunication EMFs should be drastically reduced by prudent use, and establishment of much stringer exposure limits by the responsible health authorities.