Hu C, Zuo H and Li Y (2021) Effects of Radiofrequency Electromagnetic Radiation on Neurotransmitters in the Brain. Front. Public Health 9:691880. doi: 10.3389/fpubh.2021.691880
With the rapid development of electronic information in the past 30 years, technical achievements based on electromagnetism have been widely used in various fields pertaining to human production and life. Consequently, electromagnetic radiation (EMR) has become a substantial new pollution source in modern civilization. The biological effects of EMR have attracted considerable attention worldwide. The possible interaction of EMR with human organs, especially the brain, is currently where the most attention is focused. Many studies have shown that the nervous system is an important target organ system sensitive to EMR. In recent years, an increasing number of studies have focused on the neurobiological effects of EMR, including the metabolism and transport of neurotransmitters. As messengers of synaptic transmission, neurotransmitters play critical roles in cognitive and emotional behavior. Here, the effects of EMR on the metabolism and receptors of neurotransmitters in the brain are summarized.
Extract only, for the full study see https://www.frontiersin.org/articles/10.3389/fpubh.2021.691880/full
In summary, research on the synthesis, metabolism and transport of neurotransmitters in the brain by EMR is increasing gradually, but due to the different parameters of EMR, experimental objects and conditions, the experimental results are not very consistent and comparative. Therefore, the effects of EMR on the metabolism and transport of neurotransmitters have not been clarified. Moreover, the role of neurotransmitters and their mechanism in the neurobehavioral dysfunction induced by EMR have not been revealed. Further detailed studies are needed. On the other hand, because of the complex diversity of neurotransmitters in the brain, the interaction, cotransmission and coregulation of neurotransmitters make it difficult to distinguish the primary and secondary changes of each neurotransmitter. Furthermore, the interaction of different neural nuclei in the brain constitutes sophisticated neural circuits, which is the fundamental basis of how the brain performs functions. Consequently, the regulation of neural circuits may be involved in the neurotransmitter disorder of the brain induced by EMR.