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Shift Work
Gutierrez Lopez DE, Lashinger LM, Weinstock GM, Bray MS. Circadian rhythms and the gut microbiome synchronize the host’s metabolic response to diet. Cell Metab. 2021 May 4;33(5):873-887. doi: 10.1016/j.cmet.2021.03.015. Epub 2021 Mar 30. PMID: 33789092. Abstract The molecular circadian clock and symbiotic host-microbe relationships both evolved as mechanisms that enhance metabolic responses to environmental challenges....
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Sulli G, Manoogian ENC, Taub PR, Panda S. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends in Pharmacological Sciences. 2018 Sep;39(9):812-827. DOI: 10.1016/j.tips.2018.07.003. Highlights Although circadian rhythm disruption (CRD) was typically considered to be a risk for chronic diseases solely for shift workers (∼20%...
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Hayter, E.A., Wehrens, S.M.T., Van Dongen, H.P.A. et al. Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia. Nat Commun 12, 2472 (2021). https://doi.org/10.1038/s41467-021-22788-8 Abstract Electrical activity in the heart exhibits 24-hour rhythmicity, and potentially fatal arrhythmias are more likely to occur at specific times of day. Here, we demonstrate that circadian clocks within the brain and heart set...
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Szkiela, M.; Kusideł, E.; Makowiec-Dąbrowska, T.; Kaleta, D. How the Intensity of Night Shift Work Affects Breast Cancer Risk. Int. J. Environ. Res. Public Health 2021, 18, 4570. https://doi.org/10.3390/ijerph18094570 Abstract Background—In 2019, the IARC concluded that “night shift work is probably carcinogenic to humans (Group 2A), based on limited evidence from human epidemiological studies and sufficient evidence of...
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APRIL 21, 2021 by University of Waterloo https://medicalxpress.com/news/2021-04-shift-work-negative-impacts-health-affects.html Shift-work and irregular work schedules can cause several health-related issues and affect our defense against infection, according to new research from the University of Waterloo. These health-related issues occur because the body’s natural clock, called the circadian clock, can be disrupted by inconsistent changes in the sleep-wake schedule...
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Stéphanie M. C. Abo et al. Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work, PLOS Computational Biology (2021). DOI: 10.1371/journal.pcbi.1008514 Abstract The circadian clock exerts significance influence on the immune system and disruption of circadian rhythms has been linked to inflammatory pathologies. Shift workers often experience circadian misalignment as their irregular work...
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Source: https://www.cathlabdigest.com/content/esc-heart-health-shift-workers-linked-body-clock Sophia Antipolis, April 16, 2021: Working hours that deviate from an individual’s natural body clock are associated with greater cardiovascular risk, according to research presented at ESC Preventive Cardiology 2021, an online scientific congress of the European Society of Cardiology (ESC).1 “Our study found that for each hour the work schedule was out of...
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Vieira RPO, Nehme PXSA, Marqueze EC, Amaral FG, Cipolla-Neto J, Moreno CRC. High social jetlag is correlated with nocturnal inhibition of melatonin production among night workers. Chronobiol Int. 2021 Apr 13:1-7. doi: 10.1080/07420528.2021.1912072. Epub ahead of print. PMID: 33849354. Abstract Night work can lead to social jetlag (SJL), which can be briefly defined as the...
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Woller, A.; Gonze, D. Circadian Misalignment and Metabolic Disorders: A Story of Twisted Clocks. Biology 2021, 10, 207. https://doi.org/10.3390/biology10030207AMA Style Simple Summary In mammals, many physiological processes follow a 24 h rhythmic pattern. These rhythms are governed by a complex network of circadian clocks, which perceives external time cues (notably light and nutrients) and adjusts the timing of...
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Crowther, M.E; Ferguson, S.A; Vincent, G.E; Reynolds, A.C. Non-Pharmacological Interventions to Improve Chronic Disease Risk Factors and Sleep in Shift Workers: A Systematic Review and Meta-Analysis. Clocks & Sleep 2021, 3, 132-178. https://doi.org/10.3390/clockssleep3010009 (This article belongs to the Special Issue Effects of Pre-Sleep Artificial Light on Cognition and Sleep) Abstract Shift work is associated with adverse chronic health outcomes....
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