Tag

Circadian rhythms
Chellappa SL, Vujovic N, Williams JS, Scheer FAJL. Impact of Circadian Disruption on Cardiovascular Function and Disease. Trends Endocrinol Metab. 2019 Oct;30(10):767-779. doi: 10.1016/j.tem.2019.07.008. Epub 2019 Aug 16. PMID: 31427142; PMCID: PMC6779516. Abstract The circadian system, that is ubiquitous across species, generates ∼24 h rhythms in virtually all biological processes, and allows them to anticipate...
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Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection Miguel Meira eCruz, Masaaki Miyazawa, David Gozal European Respiratory Journal Jan 2020, 2001023;  DOI: 10.1183/13993003.01023-2020 Circadian deregulation and poor or insufficient sleep may facilitate COVID19 infection and severity SARS coronavirus 2 (SARS-CoV-2), the etiologic agent of the pandemic coronavirus disease 2019 (COVID-19), is a newly found member of the Coronaviridae...
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Bato Korac, Andjelika Kalezic, Vanja Pekovic-Vaughan, Aleksandra Korac, Aleksandra Jankovic, Redox changes in obesity, metabolic syndrome, and diabetes, Redox Biology, 2021, 101887, ISSN 2213-2317,https://doi.org/10.1016/j.redox.2021.101887.(https://www.sciencedirect.com/science/article/pii/S2213231721000355) Abstract “Life is an instantaneous encounter of circulating matter and flowing energy” (Jean Giaja, Serbian physiologist), is one of the most elegant definitions not only of life but the relationship of...
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University of Colorado Denver researcher finds nighttime brightness linked to 13% increase in preterm birth likelihood 28-Jan-2021 2:15 PM EST, by University of Colorado Denver Newswise — In a first-of-its-kind study, researchers discovered that light pollution leads to more than just wasted energy and washed-out starlight–it can increase the likelihood of a preterm birth by almost 13%. Laura Argys,...
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Open Access Peer Reviewed Abstract Blood coagulation is central to myocardial ischemia and reperfusion (IR) injury. Studies on the light elicited circadian rhythm protein Period 2 (PER2) using whole body Per2-/- mice found deficient platelet function and reduced clotting which would be expected to protect from myocardial IR-injury. In contrast, intense light induction of PER2 protected from...
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Xuguang Luo, Xinhua Yang, Yanping Yang, Hairong Li, Huilin Cui & Ximei Cao (2020) The interrelationship between inflammatory cytokines and skeletal muscle decay from the viewpoint of circadian rhythms, Archives of Physiology and Biochemistry, DOI: 10.1080/13813455.2020.1782435 Abstract Circadian rhythms affect a variety of physiological processes. Disruption of circadian rhythms causes many diseases, most of which are associated with inflammation. Disruption...
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Article https://doi.org/10.1038/s41467-020-15384-9 The cyanobacterium Synechococcus elongatus is a model organism for the study of circadian rhythms. It is naturally competent for transformation—that is, it takes up DNA from the environment, but the underlying mechanisms are unclear. Here, we use a genome-wide screen to identify genes required for natural transformation in S. elongatus, including genes encoding...
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Int. J. Environ. Res. Public Health 2020, 17(2), 562; https://doi.org/10.3390/ijerph17020562 Abstract Work-related stress can induce a break in homeostasis by placing demands on the body that are met by the activation of two different systems, the hypothalamic–pituitary–adrenal axis and the sympathetic nervous system. Night-shift work alters the body’s exposure to the natural light–dark schedule and disrupts circadian (daily)...
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Front Neuroendocrinol. 2019 Dec 18:100819. doi: 10.1016/j.yfrne.2019.100819. [Epub ahead of print] Abstract Stress, primarily processed via the hypothalamic-pituitary-adrenal (HPA) axis, engages biological pathways throughout the brain and body which promote adaptation and survival to changing environmental demands. Adaptation to environmental challenges is compromised when these pathways are no longer functioning optimally. The physiological and behavioral mechanisms...
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The sky above Middelburg in the Netherlands on a past ‘Night of the Night’ Jesse Meliefste/Nacht van de Nacht Campaigners want government agencies and companies to turn off the lights so citizens can rediscover the beauty of darkness. SOPHIE KNIGHT NOVEMBER 18, 2019 AMSTERDAM—As winter creeps across the Northern Hemisphere and daylight hours dwindle, it can be...
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