Tag

Circadian Misalignment
07
Jan

G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment

January 7, 2022
Citation: Lee Y, Lahens NF, Zhang S, Bedont J, Field JM, Sehgal A (2019) G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment. PLoS Biol 17(4): e3000228. https://doi.org/10.1371/journal.pbio.3000228 Abstract Circadian disruption has multiple pathological consequences, but the underlying mechanisms are largely unknown. To address such mechanisms,...
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07
Dec

Daytime eating prevents internal circadian misalignment and glucose intolerance in night work

December 7, 2021
Daytime eating prevents internal circadian misalignment and glucose intolerance in night workSarah L. ChellappaJingyi QianNina VujovicChristopher J. MorrisArlet NedeltchevaHoa NguyenNishath RahmanSu WeiHengLauren KellyKayla Kerlin-MonteiroSuhina SrivastavWei WangDaniel AeschbachCharles A. CzeislerSteven A.SheaGail K. AdlerMarta GarauletFrank A. J. L. ScheerSci. Adv., 7 (49), eabg9910. • DOI: 10.1126/sciadv.abg9910 Abstract Night work increases diabetes risk. Misalignment between the central circadian...
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07
Oct

Communicating clocks shape circadian homeostasis

October 7, 2021
Koronowski KB, Sassone-Corsi P. Communicating clocks shape circadian homeostasis. Science. 2021;371(6530):eabd0951. doi:10.1126/science.abd0951 The publisher’s final edited version of this article is available at Science Abstract Circadian clocks temporally coordinate physiology and align it with geophysical time, enabling diverse lifeforms to anticipate daily environmental cycles. In complex organisms, clock function originates from the molecular oscillator within each cell...
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08
Aug

Circadian Rhythm and Sleep Disruption: Causes, Metabolic Consequences, and Countermeasures

August 8, 2021
Gregory D. M. Potter, Debra J. Skene, Josephine Arendt, Janet E. Cade, Peter J. Grant, Laura J. Hardie, Circadian Rhythm and Sleep Disruption: Causes, Metabolic Consequences, and Countermeasures, Endocrine Reviews, Volume 37, Issue 6, 1 December 2016, Pages 584–608, https://doi.org/10.1210/er.2016-1083 Abstract Circadian (∼24-hour) timing systems pervade all kingdoms of life and temporally optimize behavior and physiology in...
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26
Jun

Problematic Gaming and Sleep: A Systematic Review and Meta-Analysis

June 26, 2021
Kristensen J, Pallesen S, King D, Hysing M, Erevik E. Problematic Gaming and Sleep: A Systematic Review and Meta-Analysis Frontiers in Psychiatry. 2021 Jan;12.  https://doi.org/10.3389/fpsyt.2021.675237 Problematic gaming has been linked to poor sleep outcomes; however, these associations have not yet been synthesized quantitatively. This review employed a meta-analysis to investigate the relationship between problematic gaming...
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26
Jun

Sleep is essential to health: an American Academy of Sleep Medicine position statement

June 26, 2021
Kannan Ramar, Raman K. Malhotra, Kelly A. Carden, Jennifer L. Martin, Fariha Abbasi-Feinberg, R. Nisha Aurora, Vishesh K. Kapur, Eric J. Olson, Carol L. Rosen, James A. Rowley, Anita V. Shelgikar, Lynn Marie Trotti. Sleep is essential to health: an American Academy of Sleep Medicine position statement. Journal of Clinical Sleep Medicine, 2021; DOI: 10.5664/jcsm.9476 Abstract Sleep is...
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16
Jun

Sleep characteristics predict cannabis use, binge drinking in teens and young adults

June 16, 2021
Source: AMERICAN ACADEMY OF SLEEP MEDICINE NEWS RELEASE 8-JUN-2021 https://www.eurekalert.org/pub_releases/2021-06/aaos-scp060821.php DARIEN, IL – A recent study of teens and young adults found that several factors related to sleep timing and sleep duration are associated with an increased risk of cannabis use and binge drinking of alcohol during the following year. Results show that a greater late-night preference predicted...
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16
Jun

Self-Reported Sleep and Circadian Characteristics Predict Future Substance Use: A Longitudinal Analysis from the NCANDA Study

June 16, 2021
Brant Hasler, Jessica Graves, Meredith Wallace, Stephanie Claudatos, Fiona Baker, Duncan Clark, 610 Self-Reported Sleep and Circadian Characteristics Predict Future Substance Use: A Longitudinal Analysis from the NCANDA Study, Sleep, Volume 44, Issue Supplement_2, May 2021, Page A240, https://doi.org/10.1093/sleep/zsab072.608 Abstract Introduction Growing evidence indicates that sleep characteristics predict later substance use and related problems during adolescence and...
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21
Apr

Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work

April 21, 2021
Stéphanie M. C. Abo et al. Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work, PLOS Computational Biology (2021). DOI: 10.1371/journal.pcbi.1008514 Abstract The circadian clock exerts significance influence on the immune system and disruption of circadian rhythms has been linked to inflammatory pathologies. Shift workers often experience circadian misalignment as their irregular work...
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20
Apr

ESC: Heart Health of Shift Workers Linked to Body Clock

April 20, 2021,
Source: https://www.cathlabdigest.com/content/esc-heart-health-shift-workers-linked-body-clock Sophia Antipolis, April 16, 2021: Working hours that deviate from an individual’s natural body clock are associated with greater cardiovascular risk, according to research presented at ESC Preventive Cardiology 2021, an online scientific congress of the European Society of Cardiology (ESC).1 “Our study found that for each hour the work schedule was out of...
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