Stéphanie M. C. Abo et al. Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work, PLOS Computational Biology (2021). DOI: 10.1371/journal.pcbi.1008514 Abstract The circadian clock exerts significance influence on the immune system and disruption of circadian rhythms has been linked to inflammatory pathologies. Shift workers often experience circadian misalignment as their irregular work...Read More
Source: https://www.cathlabdigest.com/content/esc-heart-health-shift-workers-linked-body-clock Sophia Antipolis, April 16, 2021: Working hours that deviate from an individual’s natural body clock are associated with greater cardiovascular risk, according to research presented at ESC Preventive Cardiology 2021, an online scientific congress of the European Society of Cardiology (ESC).1 “Our study found that for each hour the work schedule was out of...Read More
Chellappa SL, Vujovic N, Williams JS, Scheer FAJL. Impact of Circadian Disruption on Cardiovascular Function and Disease. Trends Endocrinol Metab. 2019 Oct;30(10):767-779. doi: 10.1016/j.tem.2019.07.008. Epub 2019 Aug 16. PMID: 31427142; PMCID: PMC6779516. Abstract The circadian system, that is ubiquitous across species, generates ∼24 h rhythms in virtually all biological processes, and allows them to anticipate...Read More
https://www.sciencedirect.com/science/article/pii/S2451994421000043#coi0010 Abstract Night shift work is a risk factor for viral infection, suggesting that night shift schedules compromise host defense mechanisms. Prior studies have investigated changes in the temporal profiles of circulating cytokines important for priming and restraining the immune response to infectious challenges from night shift work, but not by way of a 24-h...Read More
Merikanto I, Partonen T. Increase in eveningness and insufficient sleep among adults in population-based cross-sections from 2007 to 2017. Sleep Med. 2020 Aug 19;75:368-379. doi: 10.1016/j.sleep.2020.07.046. Epub ahead of print. PMID: 32950882. Abstract Objectives: Short or long sleep duration, insufficient sleep, and Evening chronotype associate with many health issues and increased risk for mortality. Understanding population-level...Read More
