The new mechanism for gating ‘Big Potassium’ (BK) channels

Computational biophysicists are not used to making discoveries, says the senior author, so when they cracked the secret of how cells regulate Big Potassium (BK) channels, they thought it must be a computational artifact. But after many simulations and tests, they convinced themselves that they have identified the BK gating mechanism that had eluded science for many years.

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