According to the authors there is no evidence of a causal association between wireless phone use and brain tumours. Because of likely biases a small increased risk cannot be ruled out.

https://www.sciencedirect.com/science/article/pii/S0160412021006942

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Abstract

The effect of ELF-MF on human health is still controversial, particularly as regards long-term health effects like cancer. The literature does suggest, however, that they could be involved in the occurrence of brain tumors, although results concerning residential exposure are scarce. Our objective was to investigate the association between residential proximity to power lines and brain tumors among adults in France by using a geographical information system.CERENAT is a population-based case-control study carried out in France in 2004–2006. We used geographical data sources on power line location to create exposure scores based on distance between residence and power lines, and on the number of lines near residences. Conditional logistic regression for matched sets was used to estimate Odds Ratios (ORs) and 95% confidence intervals (95%CI).We found significant associations between cumulated duration living at <50 m to high voltage lines and: i) all brain tumors (OR 2.94; 95%CI 1.28–6.75); ii) glioma (OR 4.96; 95%CI 1.56–15.77). Further investigations are needed, particularly to improve the quality and availability of geographical and technical data on power lines.

Extract

Despite this study’s limitations, our results strongly suggest that the risk of brain tumor, and particularly gliomas could be associated with residential ELF-MF exposure estimated by proximity of power lines, as several previous studies have already pointed out. This study demonstrates how public cartographic data can be used in epidemiological studies to estimate residential exposure, even if they were not designed for this purpose. The limitations resulting from the original purpose of these data could be overcome by combination with other data sources, such as power line characteristics or metrology to enhance exposure assessment accuracy.

https://www.sciencedirect.com/science/article/pii/S0013935120303662?via%3Dihub

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Abstract

The National Toxicology Program tested two common radiofrequency radiation (RFR) modulations emitted by cellular telephones in a 2-year rodent cancer bioassay that included interim assessments of additional animals for genotoxicity endpoints. Male and female Hsd:Sprague Dawley SD rats and B6C3F1/N mice were exposed from Gestation day 5 or Postnatal day 35, respectively, to code division multiple access (CDMA) or global system for mobile modulations over 18 hr/day, at 10-min intervals, in reverberation chambers at specific absorption rates of 1.5, 3, or 6 W/kg (rats, 900 MHz) or 2.5, 5, or 10 W/kg (mice, 1,900 MHz). After 19 (rats) or 14 (mice) weeks of exposure, animals were examined for evidence of RFR-associated genotoxicity using two different measures. Using the alkaline (pH > 13) comet assay, DNA damage was assessed in cells from three brain regions, liver cells, and peripheral blood leukocytes; using the micronucleus assay, chromosomal damage was assessed in immature and mature peripheral blood erythrocytes. Results of the comet assay showed significant increases in DNA damage in the frontal cortex of male mice (both modulations), leukocytes of female mice (CDMA only), and hippocampus of male rats (CDMA only). Increases in DNA damage judged to be equivocal were observed in several other tissues of rats and mice. No significant increases in micronucleated red blood cells were observed in rats or mice. In conclusion, these results suggest that exposure to RFR is associated with an increase in DNA damage.

Environ. Mol. Mutagen. 61:276-290, 2020. © 2019 Wiley Periodicals, Inc.

First published 21 October 2019

Full text https://onlinelibrary.wiley.com/doi/full/10.1002/em.22343

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Authors:

• Lennart Hardell
• Michael Carlberg
• View Affiliations
• Published online on: October 24, 2018     https://doi.org/10.3892/ijo.2018.4606
• Copyright: © Hardell et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Abstract

During the use of handheld mobile and cordless phones, the brain is the main target of radiofrequency (RF) radiation. An increased risk of developing glioma and acoustic neuroma has been found in human epidemiological studies. Primarily based on these findings, the International Agency for Research on Cancer (IARC) at the World Health Organization (WHO) classified in May, 2011 RF radiation at the frequency range of 30 kHz‑300 GHz as a ‘possible’ human carcinogen, Group 2B. A carcinogenic potential for RF radiation in animal studies was already published in 1982. This has been confirmed over the years, more recently in the Ramazzini Institute rat study. An increased incidence of glioma in the brain and malignant schwannoma in the heart was found in the US National Toxicology Program (NTP) study on rats and mice. The NTP final report is to be published; however, the extended reports are published on the internet for evaluation and are reviewed herein in more detail in relation to human epidemiological studies. Thus, the main aim of this study was to compare earlier human epidemiological studies with NTP findings, including a short review of animal studies. We conclude that there is clear evidence that RF radiation is a human carcinogen, causing glioma and vestibular schwannoma (acoustic neuroma). There is some evidence of an increased risk of developing thyroid cancer, and clear evidence that RF radiation is a multi‑site carcinogen. Based on the Preamble to the IARC Monographs, RF radiation should be classified as carcinogenic to humans, Group 1.

Full paper (PDF) available:
https://www.spandidos-publications.com/10.3892/ijo.2018.4606

Related Articles

Notes by EMFSA: additional studies to consider regarding the carcinogenic classification of RFR as a Human Carcinogen.

Commentary on the utility of the National Toxicology Program study on cell phone radiofrequency radiation data for assessing human health risks despite unfounded criticisms aimed at minimizing the findings of adverse health effects https://www.sciencedirect.com/science/article/pii/S0013935118304973

Cancer epidemiology update, following the 2011 IARC evaluation of radiofrequency electromagnetic fields (Monograph 102) https://www.sciencedirect.com/science/article/pii/S0013935118303475

The post Comments on the US National Toxicology Program technical reports on toxicology and carcinogenesis study in rats exposed to whole-body radiofrequency radiation at 900 MHz and in mice exposed to whole-body radiofrequency radiation at 1,900 MHz appeared first on EMFSA.

• 20:33, 2 JUN 2018
• Updated20:38, 2 JUN 2018

Companies including Blackberry, EE, Nokia and Vodafone have told investors they could face legal action from device users if research eventually finds links between their products and cancer.

Top mobile firms are warning ­shareholders about the potential health risks of phones but keeping the information from customers.

Companies including Blackberry, EE, Nokia and Vodafone have told investors they could face legal action from device users if research eventually finds links between their products and cancer.

British Telecom, which owns EE, tells investors starkly in its 2017 annual report: “We can’t provide absolute ­assurance that research in the future won’t establish links between radio frequency emissions and health risks.”

And Nokia says: “There have been some research results that indicated the possibility that electromagnetic waves emitted from mobile devices and base stations have adverse health effects, such as increasing the risk of cancer.”

The news comes after we revealed brain cancer patient Neil Whitfield, 60, is the first Briton to sue a phone maker and could win up to £1million from Nokia if successful.

Mr Whitfield said: “If companies are warning investors there is a possible risk they should be warning people who use their phones and networks.

“They are being selective with the truth and have decided those with money are more important than the general public.”

A court in Italy recently ruled a link between tumours and mobiles and the International Agency for Research into Cancer says they are a “possible carcinogenic.”

And in France, Orange has recalled around 90,000 Hapi 30 phones because of the device’s radiation level.

Devra Davis, president of the Environmental Health Trust, said: “Financial threats from litigation are growing in step with scientific evidence linking phones to health damages.

“Further still, the Italian court ­decision indicates any firm that requires mobile use as a ­condition of work faces major liability.”

The news comes after we revealed brain cancer patient Neil Whitfield, 60, is the first Briton to sue a phone maker and could win up to £1million from Nokia if successful (Image: Sunday Mirror)

Blackberry and Nokia warn shareholders of possible legal action in reports to the US Securities and Exchange Commission.

Nokia says despite adhering to regulations “concerns over the adverse effects on health… could make it difficult to acquire and retain customers”.

Vodafone says there is “no evidence” of harm but adds: “A change to this view could result in… impacts.” Blackberry says “perceived risks” could affects sales and lead to legal battles.

Most studies find no link with cancer but others claim they increase the risk of brain cancer.

Mr Whitfield blames Nokia phones for giving him an acoustic neuroma on a nerve between his inner ear and brain.

“His case could open the floodgates and he said: “Phone companies don’t give a jot about health.”

“I’m in the autumn of my life but I worry about the next generation who spend hours each day glued to their phones.”

Nokia is fighting his claim and said safety “has always been a key consideration”, adding: “All products comply with exposure guidelines and limits set by public health ­authorities.”

More on the topic:

Mobile Phones,Brain Tumours and Court Cases

Aggressive Brain Tumors on the Rise in England

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Abstract

The post Primary brain tumors and mobile cell phone usage. appeared first on EMFSA.

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