Abstract

Epigenetic mechanisms regulate gene expression, without changing the DNA sequence, and establish cell-type-specific temporal and spatial expression patterns. Alterations of epigenetic marks have been observed in several pathological conditions, including cancer and neurological disorders. Emerging evidence indicates that a variety of environmental factors may cause epigenetic alterations and eventually influence disease risks. Humans are increasingly exposed to extremely low-frequency magnetic fields (ELF-MFs), which in 2002 were classified as possible carcinogens by the International Agency for Research on Cancer. This review summarizes the current knowledge of the link between the exposure to ELF-MFs and epigenetic alterations in various cell types. In spite of the limited number of publications, available evidence indicates that ELF-MF exposure can be associated with epigenetic changes, including DNA methylation, modifications of histones and microRNA expression. Further research is needed to investigate the molecular mechanisms underlying the observed phenomena.

https://link.springer.com/article/10.1007/s00441-021-03489-6

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Abstract

This ecological study examined whether geographical differences in the physique of Japanese children and adolescents can be explained from the perspective of photoperiodicity induced by effective day length (light duration exceeding a certain threshold of illuminance) using prefecture-level anatomical data and Mesh Climatic Data. Multiple regression analysis for height prediction demonstrated that when controlled by weight, effective day lengths of the longest and shortest months were inversely correlated with height distribution. Conversely, for weight prediction, when controlled by height, the effective day lengths of the longest and shortest months were positively correlated with weight distribution. The regression coefficients were greater for the effective day length of the shortest month in both height and weight prediction. This phenomenon where the same two explanatory variables are negatively correlated with height and positively correlated with weight in a significant manner is rare, and there may be no physiological interpretation of this phenomenon other than one based on changes in thyroid hormone signaling. These distribution characteristics are common to the photoperiodicity by which seasonal breeding vertebrates reciprocally switch thyroid hormone signaling according to prior photoperiodic history through epigenetic functions. From these perspectives, thyroid hormone signaling in a certain region was assumed to be activated in summer according to the prior shorter winter day length and inactivated in winter according to the prior longer summer day length. Regarding the prevalence of obesity, the coexistence of longer summer and winter day lengths was thought to set body composition to be short and fat in early adolescence.

https://pubmed.ncbi.nlm.nih.gov/33664773/

Copyright: © 2021 The Author(s).

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Join us for a free webinar with James Lech, doctoral candidate, multidisciplinary researcher and the recipient of numerous South African and international awards.

Topic: Pregnancy, Breastfeeding and the Interaction of EMFs

•Epigenetic domination of C-sections

•Biophysics at play in the womb

•Why do so many mothers get diastasis recti of their belly when pregnant?

•Gestational diabetes

•Autism, diabetes, and childhood cancer: epigenetic or genetic?

Date and time: Sunday 28th of February at 3pm SAST

Contact us here to attend https://www.emfsa.co.za/contact/

Images: Unsplash.com

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Prof. Paul Héroux is Professor of Toxicology and Health Effects of Electromagnetism at the McGill University. Faculty of Medicine (Department of Surgery, McGill University Health Center and InVitroPlus Laboratory).

His area of expertise:

General toxicology, in vitro toxicology of metals.

Health effects of electricity and electromagnetic fields.

His department website: http://www.invitroplus.mcgill.ca/ 

Available at the above link: Some of Prof Héroux’s  research plus a free textbook and curriculum. (A powerful and compelling read.)

He still has plenty of works not published on the site but they are highlighted in the interview.

In summary:

Prof Héroux developed a Unified Theory of Weak Magnetic Field Action that proposes A Radical New Outlook. His work has been developed, is replicable and is a total eye-opener. I will confess, when I read it months ago, I had to take many double takes because the truth of the data seems totally unbelievable to what industry literature describes. Again, all of this is true and replicable with a standard laboratory.

Additionally, we discuss how research to date has met the deterministic merit requirements for nnEMF to be labelled as a WHO IARC Type 1 carcinogen substance.

We discuss how literature tends to discriminate between non-native electromagnetic fields (nnEMF), blue light, low frequency and high frequency. Essentially, they have something in common and therefore can be lumped together in terms of their biological reaction. In this example, I will refer to how extra-low-frequency magnetic fields interact with unstable molecular structures such as hydrogen bridges, altering the ability of protons to tunnel from one molecule to another. How this plays out in practice is that the reaction rates of certain enzymes can be altered by magnetic fields at very low intensities such as 25 nT, comfortably within the range of everyday exposures. This is replicable easily in biophysics studies (nnEMF although disruptive to the cell), does not increase quickly with field intensity (power density), and drives an adaptation of the cell to the radiation. Metabolism is altered because one enzyme, ATP Synthase, is particularly vulnerable: the ratio between glycolysis and redox metabolism is changed. The mechanism also extends to RF frequencies, implicating all broadcasting and radiating telecommunications systems. Hence, why nnEMF impacts chronic disease rates such as cancer, obesity diabetes, neurological disorders and autoimmune diseases (basically everything epigenetic).

The simpler explanation:

We are taught to believe 100% that everything is tied to diet and exercise. However, it is exactly the opposite. We are taught to think about obesity as excess calories. Yet, when using Albert Einstein’s equations, and in this example E = MC2 (number 2 must be super scripted), when reading his equation in reverse, it says obesity is a disease of a loss of electrons. Stop thinking of food as carbs, proteins, and fats, and instead think of them as electrons that move protons across membranes in cells. The brain is a quantum computer and processes food as such.

Think of your body as a car, if it were a Porche, what is more important, ensuring how the car performing under the hood or worrying if 93 or 95 octane is going into it? nnEMFs puts your car’s performance and function out of whack.

Additionally, with genetic tests into nnEMF reactions to the body, a 2014 study by De Luca et al. found a large percentage of the population lacking the enzyme to detox nnEMF effectively, and even with those that do, persons would have different efficiency rates.

Based on the above, there is a syndrome of symptoms and diseases experienced by the population with the associated score of Neolithic diseases. Quantum biology uses the principles of physics to explain the biological processes. This is demonstrable when using mitigation options from the understanding of biophysics that results are very noticeable. For example, being able to lose 35kg in 3 months without any exercise and calorie counting, or seeing massive improvements in diabetes or thyroid issues.

The problems with nnEMF exposures is that it is not like engineering where we can flick off a switch and therefore the problem. The effects can be permanent and evident. A well-conducted epidemiology study in California assessed pregnant mothers with exposures greater than 2.5 millGauss.

The results showed:

  3 times increased risk incidence for, miscarriage, asthma in offspring, ADHD, abnormal thyroid function

  5 times increased the risk of obesity in offspring. 

However, the WHO IARC assessment found the incidence of childhood leukaemia in as low as 1 mG.

Super Dads – Prof. Paul Héroux

Note to our readers: EMFSA added the video below to the notes about the podcast.

Dr. Paul Heroux Testifies at Michigan’s 5G Small Cell Tower Legislation Hearing October 4, 2018

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Contemporary Mobile Technology and Child and Adolescent Development,
edited by Zheng Yan and Lennart Hardell, May 15, 2017

Article by
Cindy Sage and Ernesto Burgio

Abstract

Mobile phones and other wireless devices that produce electromagnetic fields (EMF) and pulsed radiofrequency radiation (RFR) are widely documented to cause potentially harmful health impacts that can be detrimental to young people. New epigenetic studies are profiled in this review to account for some neurodevelopmental and neurobehavioral changes due to exposure to wireless technologies. Symptoms of retarded memory, learning, cognition, attention, and behavioral problems have been reported in numerous studies and are similarly manifested in autism and attention deficit hyperactivity disorders, as a result of EMF and RFR exposures where both epigenetic drivers and genetic (DNA) damage are likely contributors. Technology benefits can be realized by adopting wired devices for education to avoid health risk and promote academic achievement.

Citation Sage, C. and Burgio, E. (2017), Electromagnetic Fields, Pulsed Radiofrequency Radiation, and Epigenetics: How Wireless Technologies May Affect Childhood Development. Child Dev. doi:10.1111/cdev.12824

Contact Correspondence concerning this article should be addressed to Cindy Sage, Sage Associates,
1396 Danielson Road, Santa Barbara, CA 93108. Electronic mail may be sent to sage@silcom.com.

Discussion

The wide array of pathophysiological effects of EMF and RFR exposures from wireless sources do not require “the breaking of molecular bonds” as done by ionizing radiation in order for physiologically damaging effects to occur. Epigenetic mechanisms alone can change fetal development in profound ways, disrupting health by causing changes in gene activation and expression without change in gene sequences. Environmental epigenetic influences in the fetal and neonatal development (i.e., epigenetic regulation of genes rather than direct genetic effects by gene mutation) have been plausibly established to cause pathophysiological changes that can result in altered neurological development. Symptoms of neurodevelopmental problems in children like retarded memory, impaired learning, cognition, attention, and behavioral aberrations that are similarly expressed in autism and ADHD have been reported in numerous scientific studies to occur as a result of EMF and RFR exposures. Epigenetic drivers are the most likely causes, and persistent exposures contribute to chronic dysfunction and addiction that can overwhelm adaptive biological responses.

Epigenetics provides an under-recognized mechanism for the cell phone radiation damage seen in epidemiological studies on humans, and in animal toxicity studies. Epigenetics is redefining the traditional interpretations of ‘Mendelian genes and genetic inheritance’, and legitimizing mechanisms that account for health effects that are already epidemiologically visible.

Epigenetic mechanisms rebut the outdated thinking for experts like David Savitz, a leading US epidemiologist to argue that ” (C)ell phones (and to a lesser extent cordless phones) give off non-ionizing radiation, which unlike ionizing radiation such as X-rays, CT scans and radon do not have the potential to damage DNA. “There is no known pathway for any adverse health effects,” http://www.cnn.com/2015/07/28/health/cell-phones- brain-tumor- risk-berkeley/

Global saturation by wireless device emissions is our largest modifiable and preventable childhood contaminant. It may exacerbate health harm from chemical toxins such as environmental tobacco, mercury, lead and pthalate toxicity that already burden the developing child. We should think first of reducing the body-burden of wireless emissions which cause epigenetic changes leading to cognitive and behavioral issues in the young child, as well as the underlying neurodevelopmental problems of the fetus, before widely prescribing chemical and/or behavioral interventions.

Public health experts, educators and psychologists have gained a strong new tool to argue against pulsed radiofrequency radiation saturation by wireless devices and infrastructure. Wireless exposures are modifiable and largely avoidable by choosing wired for technology access. This may hold the largest potential for global preventative health action we have. In comparison to chemical toxicants and other neurotoxins and neurodevelopmental contaminants, we have a clear and immediate choice to avoid wireless technologies in favor of wired connectivity. Prevention of environmental exposures that can lead to disease and developmental disabilities is within reach, now that we are coming to understand how epigenetic mechanisms can modify the expression of the human genome. http://www.bioinitiative.org/how-wireless-technologies-may-affect-childhood-development/

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Anne Sophie Lapix, presenter of the program, refers to Prof. Belpomme’s newest book, “Comment naissent les maladies” [how do diseases arise?] where he says 70-90% of cancers are linked to the environment.

The post Summary of French TV Program “C à vous” : Interview with Professor Dominique Belpomme appeared first on EMFSA.